Role of an automated screening tool for familial hypercholesterolemia in patients with premature coronary artery disease.

ABSTRACT:

Background and aims

To validate an automated screening tool for patients with premature coronary artery disease (CAD) and high total cholesterol or LDL-C levels and assess if it would provide clinicians with additional support in identifying patients with Familial Hypercholesterolemia (FH).

Methods

An IT-based automated screening tool based on coronary angiography data recorded in the KARDIO registry and laboratory values was validated among patients undergone coronary angiography in the Heart Hospital at Tampere University Hospital between 2007 and 2017 fulfilling the criteria of premature CAD (men <55 years and women <60 years) and history of high total cholesterol (>8 mmol/l) or LDL-cholesterol (>5 mmol/l) levels. Electronic health records were retrospectively analyzed to

SUBMITTER: Jokiniitty A 

PROVIDER: S-EPMC9833226 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature