Assessing the determinants of completing OAT induction and long-term retention: A population-based study in British Columbia, Canada.

ABSTRACT:

Background

Pharmacological treatments for opioid use disorder are essential, life-saving medications, yet successful induction of them and long-term retention on them is limited in many settings. Induction into opioid agonist treatment (OAT) features the highest risk of mortality throughout the treatment course, and greatest risk of discontinuation. We aimed to identify determinants of completing OAT induction and, among those completing induction, time to OAT discontinuation in British Columbia (BC), Canada.

Methods

We conducted a retrospective study using linked population-level health administrative databases to capture all individuals in BC receiving at least one OAT dispensation from January 1, 2008, to September 30, 2018. We constructed covariates capturing client demo

SUBMITTER: Kurz M 

PROVIDER: S-EPMC9833672 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature