Salmonella enterica serovars in absence of ttrA and pduA genes enhance the cell immune response during chick infections.

ABSTRACT: Salmonella spp. is one of the major foodborne pathogens responsible for causing economic losses to the poultry industry and bringing consequences for public health as well. Both the pathogen survival ability in the intestinal environment during inflammation as well as their relationship with the host immune system, play a key role during infections in poultry. The objective of this study was to quantify the presence of the macrophages and CD4⁺/CD8⁺ cells populations using the immunohistochemistry technique, in commercial lineages of chickens experimentally infected by wild-type and mutant strains of Salmonella Enteritidis and Salmonella Typhimurium lacking ttrA and pduA genes. Salmonella Enteritidis ∆ttrA∆pduA triggered a higher percentage of the stained area than the

SUBMITTER: Cabrera JM 

PROVIDER: S-EPMC9834210 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature