Migraine Type-Dependent Patterns of Brain Activation After Facial and Intranasal Trigeminal Stimulation.

ABSTRACT: In migraine, the trigeminal nerve is intimately involved in the pathophysiology of the disease. We hypothesized that alterations in the sensory trigeminal activation in migraine would be reflected by EEG-derived event-related potentials (ERP). We aimed to investigate differences in the temporal and spatial processing of trigeminal stimuli between interictal migraine patients and healthy subjects. ERP to trigeminal stimuli were recorded at 128-channels to allow localization of their cortical sources with high temporal resolution. Seventeen patients with episodic migraine without aura, 17 subjects with episodic migraine with aura, and 17 healthy subjects participated in the study. The first branch of the trigeminal nerve was stimulated using intranasal chemical (CO₂), cutaneous el

SUBMITTER: Haehner A 

PROVIDER: S-EPMC9834371 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature