Effectiveness of Intranasal Tear Neurostimulation for Treatment of Dry Eye Disease: A Meta-Analysis.

ABSTRACT:

Introduction

To assess the effectiveness and safety of intranasal tear neurostimulation in the treatment of dry eye disease.

Methods

We performed a meta-analysis of four databases from their inception to October 2022 without language restrictions. Randomized controlled trials and non-randomized controlled trials meeting the inclusion criteria were included in this review and were quality appraised. The risk of bias was evaluated by two independent reviewers using the Cochrane Collaboration Tool and Methodological Index for Non-Randomized Studies. The random-effect model or fixed-effect model was adopted to estimate the pooled effect sizes.

Results

Fifteen published studies consisting of 17 clinical trials with a total of 901 patients were analyzed. Schirmer II test sc

SUBMITTER: Li Z 

PROVIDER: S-EPMC9834483 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature