A novel nomogram predicting cancer-specific survival in small cell lung cancer patients with brain metastasis.

ABSTRACT:

Background

Brain metastasis (BM) is one of the most common metastatic sites in patients with small cell lung cancer (SCLC), and the prognosis remains very poor. This study aimed to establish a novel nomogram for predicting the cancer-specific survival (CSS) in SCLC patients with BM.

Methods

SCLC patients with BM from the Surveillance, Epidemiology, and End Results (SEER) database between 2010 and 2015 were retrospectively collected. Univariate and multivariate Cox regression analyses were performed to identify independent prognostic factors, which were further used to construct the prognostic nomogram. The discrimination and calibration of nomogram were evaluated by concordance index (C-index), receiver operating characteristic (ROC) curve, the area under ROC curve (AUC) and

SUBMITTER: Rong YT 

PROVIDER: S-EPMC9834596 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature