Chemotherapy exacerbates the survival paradox of colon cancer: a propensity score matching analysis.

ABSTRACT:

Background

Colon cancer is one of the most common tumor diseases in the world. Currently, clinicians usually evaluate the survival and prognosis of patients according to their tumor-node-metastasis (TNM) stage. However, current studies have found that there is a certain survival paradox in TNM staging.

Methods

In the Surveillance, Epidemiology, and End Results (SEER) database, patients diagnosed with colon cancer by surgical pathology from 2004 to 2011 were selected for analysis of 5-year overall survival (OS). Propensity score matching (PSM) was performed to analyze the difference in survival between different stages and the effect of chemotherapy on prognosis.

Results

The OS of stage IIIA colon cancer sufferers was significantly superior to stage IIB/IIC and separat

SUBMITTER: Tian M 

PROVIDER: S-EPMC9834597 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature