Serum diagnostic markers for malignant pleural mesothelioma: a narrative review.

ABSTRACT:

Background and objective

The prognosis of patients with malignant pleural mesothelioma (MPM) is poor, and early diagnosis is key to improving the prognosis. Pleural biopsy is the gold reference for diagnosing MPM, but it is an invasive method that can cause operation-related complications such as bleeding and infection. Serum biomarkers, with the advantages of mini-invasiveness, short turnaround time and objectiveness, represent a promising diagnostic tool for MPM.

Methods

We searched the PubMed database to identify clinical studies published between 1990 to July 2022 that investigated the diagnostic accuracy of serum biomarkers for MPM. The major findings of the verified studies were summarized.

Key content and findings

Currently, there are many available serum marke

SUBMITTER: Wang JJ 

PROVIDER: S-EPMC9834602 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature