Usefulness of endocytoscopy in evaluating transbronchial biopsy specimens.

ABSTRACT:

Background

Endocytoscopy (ECS) provides a magnification of approximately 450× for real-time observation of lesion nuclei. Using ECS, we aimed to evaluate whether sufficient samples for diagnosis can be obtained during bronchoscopy. We also investigated whether ECS can enable two-class diagnosis of malignant or non-malignant transbronchial biopsy specimens in real-time during bronchoscopy.

Methods

This was a single-facility, prospective, observational, ex vivo study. Forty cases with localized peripheral pulmonary lesions underwent transbronchial biopsy with endobronchial ultrasonography using a guide sheath. Each biopsy specimen was immediately observed and evaluated endocytoscopically after the collection by the bronchoscopic procedure.

Results

Thirty-seven cases wer

SUBMITTER: Okuno T 

PROVIDER: S-EPMC9834692 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature