Botulinum Toxin A in the Management of Pediatric Sialorrhea: A Systematic Review.

ABSTRACT:

Objective

Botulinum toxin A is known to be effective and safe in managing sialorrhea in pediatric patients; however, there is no consensus on a protocol for optimal injection sites and appropriate dosing for injection.

Methods

This review was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol. PubMed, EMBASE, and other databases were queried to identify articles that evaluated botulinum toxin type A for the treatment of sialorrhea in the pediatric population. A total of 405 studies were identified. After applying inclusion and exclusion criteria, 31 articles were included for review.

Results

A total of 14 studies evaluated 2-gland injections, and 17 studies evaluated 4-gland injections. Of the 31 studies included, one study

SUBMITTER: Heikel T 

PROVIDER: S-EPMC9834812 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature