Immunotherapy for the treatment of pediatric brain tumors: a narrative review.

ABSTRACT:

Background and objective

The goal of this narrative review is to report and summarize the completed pediatric immunotherapy clinical trials for primary CNS tumors. Pediatric central nervous system (CNS) tumors are the most common cause of pediatric solid cancer in children aged 0 to 14 years and the leading cause of cancer mortality. Survival rates for some pediatric brain tumors have improved, however, there remains a large portion of pediatric brain tumors with poor survival outcomes despite advances in treatment. Cancer immunotherapy is a growing field that has shown promise in the treatment of pediatric brain tumors that have historically shown a poor response to treatment. This narrative review provides a summary and discussion of the published literature focused on treating p

SUBMITTER: Shalita C 

PROVIDER: S-EPMC9834947 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature