Preliminary study on intravoxel incoherent motion imaging and diffusion kurtosis imaging based on magnetic resonance imaging of normal kidneys in children.

ABSTRACT:

Background

Renal disease in children may lead to a continuous decline of renal function. Multimodal functional magnetic resonance imaging (fMRI) technology can provide quantitative evaluation of renal function information. We investigated the feasibility of intravoxel incoherent motion imaging (IVIM) and diffusion kurtosis imaging (DKI) based on 3.0T MRI for the assessment of normal renal function in children and then analyzed the changes in functional parameters during development.

Methods

A total of 132 children with normal function of both kidneys were grouped according to age: ≤1 year old, 1-≤2 years old, 2-≤3 years old, 3-≤10 years old, and 10-≤14 years old. All subjects received renal IVIM examinations to obtain the measured values of true diffusion coefficient (D), ps

SUBMITTER: Yan Z 

PROVIDER: S-EPMC9834948 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature