Intranasal antisepsis to reduce influenza virus transmission in an animal model.

ABSTRACT:

Background

Seasonal influenza annually causes significant morbidity and mortality, and unpredictable respiratory virus zoonoses, such as the current COVID-19 pandemic, can threaten the health and lives of millions more. Molecular iodine (I₂ ) is a broad-spectrum, pathogen-nonspecific antiseptic agent that has demonstrated antimicrobial activity against a wide range of bacteria, virus, and fungi.

Methods

We investigated a commercially available antiseptic, a non-irritating formulation of iodine (5% povidone-iodine) with a film-forming agent that extends the duration of the iodine's antimicrobial activity, for its ability to prevent influenza virus transmission between infected and susceptible animals in the guinea pig model of influenza virus transmission.

Resul

SUBMITTER: Gaaloul Ben Hnia N 

PROVIDER: S-EPMC9835424 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature