Regular cannabis use modulates the impact of HIV on the neural dynamics serving cognitive control.

ABSTRACT:

Background

Cannabis use and HIV are independently associated with decrements in cognitive control. However, the combined effects of HIV and regular cannabis use on the brain circuitry serving higher-order cognition are unclear.

Aims

Investigate the interaction between cannabis and HIV on neural interference effects during the flanker task and spontaneous activity in regions underlying higher-order cognition.

Methods

The sample consisted of 100 participants, including people with HIV (PWH) who use cannabis, PWH who do not use cannabis, uninfected cannabis users, and uninfected nonusers. Participants underwent an interview regarding their substance use history and completed the Eriksen flanker task during magnetoencephalography (MEG). MEG data were imaged in the time-fr

SUBMITTER: Schantell M 

PROVIDER: S-EPMC9835727 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature