Reconsidering the Utility of Race-Specific Lung Function Prediction Equations.

ABSTRACT: Rationale: African American individuals have worse outcomes in chronic obstructive pulmonary disease (COPD). Objectives: To assess whether race-specific approaches for estimating lung function contribute to racial inequities by failing to recognize pathological decrements and considering them normal. Methods: In a cohort with and at risk for COPD, we assessed whether lung function prediction equations applied in a race-specific versus universal manner better modeled the relationship between FEV₁, FVC, and other COPD outcomes, including the COPD Assessment Test, St. George's Respiratory Questionnaire, computed tomography percent emphysema, airway wall thickness, and 6-minute-walk test. We related these outcomes to differences in FEV₁ using multiple

SUBMITTER: Baugh AD 

PROVIDER: S-EPMC9836221 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature