Evolution and codon usage bias of mitochondrial and nuclear genomes in Aspergillus section Flavi.

ABSTRACT: The fungal genus Aspergillus contains a diversity of species divided into taxonomic sections of closely related species. Section Flavi contains 33 species, many of industrial, agricultural, or medical relevance. Here, we analyze the mitochondrial genomes (mitogenomes) of 20 Flavi species-including 18 newly assembled mitogenomes-and compare their evolutionary history and codon usage bias patterns to their nuclear counterparts. Codon usage bias refers to variable frequencies of synonymous codons in coding DNA and is shaped by a balance of neutral processes and natural selection. All mitogenomes were circular DNA molecules with highly conserved gene content and order. As expected, genomic content, including GC content, and genome size differed greatly between mitochondrial and nuclear genomes

SUBMITTER: Hugaboom M 

PROVIDER: S-EPMC9836360 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature