Facility Volume as a Prognosticator of Survival in Locally Advanced Papillary Thyroid Cancer.

ABSTRACT:

Objectives

To evaluate the influence of facility case-volume on survival in patients with locally advanced papillary thyroid cancer (PTC), and to identify prognostic case-volume thresholds for facilities managing this patient population.

Study design

Retrospective database study.

Methods

The 2004-2017 National Cancer Database was queried for patients receiving definitive surgery for locally advanced PTC. Using K-means clustering and multivariable Cox proportional-hazards (CPH) regression, two groups with distinct spectrums of facility case-volumes were generated. Multivariable CPH regression and Kaplan-Meier analysis assessed for the influence of facility case-volume and the prognostic value of its stratification on overall survival (OS).

Results

Of 48,899 pati

SUBMITTER: Abiri A 

PROVIDER: S-EPMC9837308 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature