The Risk of Adverse Events in Smokers Undergoing Spinal Fusion: A Systematic Review and Meta-Analysis.

ABSTRACT:

Study design

Systematic review and meta-analysis.

Objectives

Determine if tobacco use is associated with increased risk of postoperative adverse events within 90 days in patients undergoing spinal fusion surgery.

Methods

Databases were queried to identify cohort studies that directly compared smokers with non-smokers and provided the absolute number of adverse events and the population at risk. Data quality was evaluated using the Quality in Prognosis Studies tool. Risk ratios (RR) and 95% confidence intervals were calculated and compared between studies. The grading of recommendation, assessment, development and evaluation (GRADE) criteria were used to assess the strength of the evidence.

Results

Seventeen studies assessing 37 897 participants met the inclusio

SUBMITTER: Nunna RS 

PROVIDER: S-EPMC9837502 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature