Maternal fluoride exposure, fertility and birth outcomes: The MIREC cohort.

ABSTRACT:

Objective

Fluoride exposure >1.5 mg/L from water has been associated with adverse pregnancy and birth outcomes. Little is known, however, about the effect of fluoride at levels consistent with water fluoridation (i.e., 0.7 mg/L) on pregnancy and birth outcomes. We examined the relationship between maternal fluoride exposure, fertility, and birth outcomes in a Canadian pregnancy cohort living in areas where municipal drinking water fluoride concentrations ranged from 0.04 to 0.87 mg/L.

Methods

Using data from the Maternal-Infant Research on Environmental Chemicals (MIREC) study, we estimated fluoride exposure during pregnancy using three different metrics: (1) maternal urinary fluoride concentrations standardized for specific gravity (MUF_SG) and averaged across all

SUBMITTER: Goodman C 

PROVIDER: S-EPMC9837859 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature