Long-term air pollution exposure and incident stroke in American older adults: A national cohort study.

ABSTRACT:

Aims

Stroke is a leading cause of death and disability for Americans, and growing evidence suggests that air pollution may play an important role. To facilitate pollution control efforts, the National Academy of Sciences and the World Health Organization have prioritized determining which air pollutants are most toxic. However, evidence is limited for the simultaneous effects of multiple air pollutants on stroke.

Methods and results

We constructed a nationwide population-based cohort study, using the Medicare Chronic Conditions Warehouse (2000-2017) and high-resolution air pollution data, to investigate the impact of long-term exposure to ambient PM_2.5, NO₂, and ground-level O₃ on incident stroke. Hazard ratios (HR) for stroke incidence were

SUBMITTER: Ma T 

PROVIDER: S-EPMC9838077 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature