High flow nasal oxygen and awake prone positioning - Two allies against COVID-19: A systematic review.

ABSTRACT:

Introduction

Severe acute respiratory distress syndrome coronavirus disease-2 (SARS-CoV-2) can lead to acute hypoxemic respiratory failure (AHRF) with possible multisystemic involvement. Ventilation/perfusion mismatch and shunt increase are critical determinants of hypoxemia. Understanding hypoxemia and the mechanisms involved in its genesis is essential to determine the optimal therapeutic strategy. High flow nasal oxygen (HFNO) and awake prone positioning (APP) in patients with COVID-19 AHRF showed promising benefits. The aim of this systematic review was to depict current situation around the combined use of HFNO and APP in patients with COVID-19 AHRF. Particularly, to investigate and report the pathophysiological rationale for adopting this strategy and to evaluate the (1) crit

SUBMITTER: Godoy DA 

PROVIDER: S-EPMC9838094 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature