Simultaneous Detection of Hypochlorite and Singlet Oxygen by a Thiocoumarin-Based Ratiometric Fluorescent Probe.

ABSTRACT: The development of fluorescent probes derived from thiocarbonyl compounds for reactive oxygen species has been actively pursued in recent years. However, a better understanding of the optical response behaviors of thiocarbonyl compounds toward reactive oxygen species remains a challenge. Along with this, further studies to overcome the limitation of a single emission channel and aggregation-caused quenching features of thiocarbonyl-based fluorescent probes are highly desirable. Due to the important role of hypochlorite and singlet oxygen in biological processes and their common coexistence in living systems with frequent intertransformations, the design of a fluorescent probe that can recognize both hypochlorite and singlet oxygen is of great interest. Herein, a thiocarbonyl-based ratiomet

SUBMITTER: Cho M 

PROVIDER: S-EPMC9838813 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature