Effect of adipose derived stromal vascular fraction on leprosy neuropathy: A Preliminary report.

ABSTRACT:

Background

Adipose derived stromal vascular fraction (SVF) contains a heterogeneous population of mononuclear cells, progenitor cells and about 1-10% are mesenchymal stromal cells. These cells are an ideal candidate for regenerative medicine for peripheral neuropathy. Leprosy is a disabling disorder with neuropathy, usually with consequences of permanent disability of the extremities. We conducted a preliminary study to evaluate the cell yield, its characteristics and clinical outcomes after SVF injections in four leprosy patients.

Methods

Four post leprosy patients were recruited and evaluated for sensory testing (warm detection, cold detection, vibration, pain and sensation) on the ulnar area of the hand. Liposuction was done and adipose tissue was processed into SVF with

SUBMITTER: Sirait SP 

PROVIDER: S-EPMC9838844 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature