Impact of Enterococcus faecalis Endocarditis Treatment on Risk of Relapse.

ABSTRACT:

Background

Enterococcus faecalis infective endocarditis (EFIE) is characterized by a higher frequency of relapses than other infective endocarditis. The role of the treatment on its occurrence remains poorly understood. The aim of this study was to investigate whether the antibiotic regimen could impact the risk of relapse in EFIE.

Materials

This was a multicenter retrospective study of patients diagnosed with definite EFIE between 2015 and 2019 in 14 French hospitals. The primary endpoint was the occurrence of relapses within the year following endocarditis diagnosis. As death was a competing risk for relapse, Fine and Gray models were used for studying risk factors and impact of treatment.

Results

Of the 279 patients included, 83 (29.7%) received the amoxicillin-gen

SUBMITTER: Danneels P 

PROVIDER: S-EPMC9839190 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature