Cost-effectiveness of population screening for atrial fibrillation: the STROKESTOP study.

ABSTRACT:

Aims

Previous studies on the cost-effectiveness of screening for atrial fibrillation (AF) are based on assumptions of long-term clinical effects. The STROKESTOP study, which randomised 27 975 persons aged 75/76 years into a screening invitation group and a control group, has a median follow-up time of 6.9 years. The aim of this study was to estimate the cost-effectiveness of population-based screening for AF using clinical outcomes.

Methods and results

The analysis is based on a Markov cohort model. The prevalence of AF, the use of oral anticoagulation, clinical event data, and all-cause mortality were taken from the STROKESTOP study. The cost for clinical events, age-specific utilities, utility decrement due to stroke, and stroke death was taken from the literature. Uncerta

SUBMITTER: Lyth J 

PROVIDER: S-EPMC9839418 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature