Early pregnancy essential and non-essential metal mixtures and maternal antepartum and postpartum depressive symptoms.

ABSTRACT:

Background

Mood disorders are common during and after pregnancy, and environmental metals may contribute to increased risk. Antepartum metal exposures have not been well characterized in relation to maternal depression. We evaluated the extent to which early pregnancy erythrocyte concentrations of essential and non-essential metals were prospectively associated with antepartum and postpartum depressive symptoms.

Methods

Participants were 1226 women in Project Viva, a longitudinal cohort recruited during pregnancy (1999-2002). We measured concentrations of 11 metals in maternal first trimester erythrocytes (arsenic, barium, cadmium, cesium, copper, mercury, magnesium, manganese, lead, selenium, zinc). Using the Edinburgh Postnatal Depression Scale (EPDS), we assessed elevated

SUBMITTER: Rokoff LB 

PROVIDER: S-EPMC9839522 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature