Prospective Association of Daily Steps With Cardiovascular Disease: A Harmonized Meta-Analysis.

ABSTRACT:

Background

Taking fewer than the widely promoted "10 000 steps per day" has recently been associated with lower risk of all-cause mortality. The relationship of steps and cardiovascular disease (CVD) risk remains poorly described. A meta-analysis examining the dose-response relationship between steps per day and CVD can help inform clinical and public health guidelines.

Methods

Eight prospective studies (20 152 adults [ie, ≥18 years of age]) were included with device-measured steps and participants followed for CVD events. Studies quantified steps per day and CVD events were defined as fatal and nonfatal coronary heart disease, stroke, and heart failure. Cox proportional hazards regression analyses were completed using study-specific quartiles and hazard ratios (HR) and 95%

SUBMITTER: Paluch AE 

PROVIDER: S-EPMC9839547 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature