Analysis of Local Control Outcomes and Clinical Prognostic Factors in Localized Pelvic Ewing Sarcoma Patients Treated With Radiation Therapy: A Report From the Children's Oncology Group.

ABSTRACT:

Purpose

To identify potential clinical prognostic factors associated with a higher risk of local recurrence in patients with localized pelvic Ewing sarcoma treated with radiation therapy.

Methods and materials

Data for 101 patients treated with definitive radiation therapy (RT) or both surgery and radiation (S + RT) to primary pelvic tumors on INT-0091, INT-0154, and AEWS0031 were analyzed. Imaging data for patients who did not receive radiation were not available for central review; therefore, patients with surgery alone were not included. Cumulative incidence rates for local failure at 5 years from time of local control were calculated accounting for competing risks.

Results

The most common pelvic subsite was sacrum (44.6%). RT was used in 68% of patients and S + RT

SUBMITTER: Ahmed SK 

PROVIDER: S-EPMC9839580 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature