Ontology highlight
ABSTRACT:
SUBMITTER: Yang Z
PROVIDER: S-EPMC9839716 | biostudies-literature | 2023 Jan
REPOSITORIES: biostudies-literature
Yang Zhan Z Wang Ya-Xuan YX Wen Jin-Kun JK Gao Hai-Tao HT Han Zhen-Wei ZW Qi Jin-Chun JC Gu Jun-Fei JF Zhao Chen-Ming CM Zhang Hong H Shi Bei B Wang Dan-Dan DD Wang Xiao-Lu XL Qu Chang-Bao CB
Cell death & disease 20230113 1
Splicing factor 3B subunit 4 (SF3B4) plays important functional roles not only in pre-mRNA splicing, but also in the regulation of transcription, translation, and cell signaling, and its dysregulation contributes to various diseases including Nager syndrome and tumorigenesis. However, the role of SF3B4 and underlying mechanisms in clear cell renal cell carcinoma (ccRCC) remain obscure. In the present study, we found that the expression of SF3B4 was significantly elevated in ccRCC tissues and neg ...[more]