Blood-Coagulation-Inspired Dynamic Bridging Strategy for the Fabrication of Multiscale-Assembled Hierarchical Porous Material.

ABSTRACT: Porous materials, from macroscopic bulk materials (MBs) with (sub-)millimeter-scale pores to tiny particles (TPs) with (sub-)nanometer-scale pores, have attracted ever-growing interest in various fields. However, the integration of multi-scale pores in one composite is promising but challenging, owing to the considerable gap in the scale of the pores. Inspired by blood coagulation, a fibrin-based dynamic bridging strategy is developed to fabricate a multiscale-assembled hierarchical porous material (MHPM), in which fibrin formed as the sub-framework for the weaving-narrow of MBs and the enwinding-load of TPs. The bio-polymerization nature makes the fabrication rapid, facile, and universal for the customizable integration of seven kinds of TPs and four kinds of MBs. Besides, the integration

SUBMITTER: Zhang L 

PROVIDER: S-EPMC9839836 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature