Oligoprogression in non-small cell lung cancer: a narrative review.

ABSTRACT:

Background and objective

Non-small cell lung cancer (NSCLC) accounts for 80% of lung cancers and is the most common non-cutaneous cancer world-wide. In NSCLC, oligometastatic and oligoprogressive disease (OPD) have been recognized as separate entities within the realm of metastatic disease and are emerging concepts in the context of targeted systemic therapies. Our objectives are to discuss the current literature regarding the evolving definitions of OPD in the context of oligometastatic disease (OMD) for NSCLC. Further, to discuss current and future clinical trials that have shaped our local approach with stereotactic body radiation therapy (SBRT)/stereotactic ablative radiotherapy (SABR).

Methods

Literature on OPD in NSCLC and local ablative therapy (LAT) including SBRT/SA

SUBMITTER: Nguyen KT 

PROVIDER: S-EPMC9840049 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature