Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review.

ABSTRACT: Neurodevelopmental disorders - including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, communication disorders, intellectual disability, motor disorders, specific learning disorders, and tic disorders - manifest themselves early in development. Valid, reliable and broadly usable biomarkers supporting a timely diagnosis of these disorders would be highly relevant from a clinical and public health standpoint. We conducted the first systematic review of studies on candidate diagnostic biomarkers for these disorders in children and adolescents. We searched Medline and Embase + Embase Classic with terms relating to biomarkers until April 6, 2022, and conducted additional targeted searches for genome-wide association studies (GWAS) and neuroimaging or neurophysiologi

SUBMITTER: Cortese S 

PROVIDER: S-EPMC9840506 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature