Gait in cerebral small vessel disease, pre-dementia, and dementia: A systematic review.

ABSTRACT:

Background

The interrelationships between gait, cerebral small vessel disease (CSVD), and cognitive impairments in aging are not well-understood-despite their common co-occurrence.

Objective

To systematically review studies of gait impairment in CSVD, pre-dementia, and dementia, and to identify key gaps for future research and novel pathways toward intervention.

Methods

A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-guided search strategy was implemented in PubMed to identify relevant studies. Potential articles (n = 263) published prior to 1 December 2021 were screened by two reviewers. Studies with sample sizes >20 and including some adults over > 65 years (n = 202) were included.

Results

The key findings were that (1) adverse g

SUBMITTER: Blumen HM 

PROVIDER: S-EPMC9841467 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature