Efficacy and safety of long-term use of a positive expiratory pressure device in chronic obstructive pulmonary disease patients, a randomized controlled trial.

ABSTRACT:

Background

Exercise intolerance is among the most common symptoms experienced by patients with chronic obstructive pulmonary disease (COPD), which is associated with lung dynamic hyperinflation (DH). There was evidence that positive expiratory pressure (PEP), which could be offered by less costly devices, could reduce DH. The purpose of this study was to evaluate the efficacy and safety of long-term domiciliary use of PEP device in subjects with COPD.

Methods

A randomized controlled trial was conducted and 25 Pre-COPD or mild-to-very severe subjects with COPD were randomized to intervention group (PEP device, PEP = 5 cmH₂O, n = 13) and control group (Sham-PEP device, PEP = 0 cmH₂O, n = 12). PEP device was a spring-loaded resistor face mask. Subjects wer

SUBMITTER: Xu Z 

PROVIDER: S-EPMC9841661 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature