Development of the gut microbiota during early life in premature and term infants.

ABSTRACT:

Background

The gastrointestinal (GI) microbiota has been linked to health consequences throughout life, from early life illnesses (e.g. sepsis and necrotising enterocolitis) to lifelong chronic conditions such as obesity and inflammatory bowel disease. It has also been observed that events in early life can lead to shifts in the microbiota, with some of these changes having been documented to persist into adulthood. A particularly extreme example of a divergent early GI microbiota occurs in premature neonates, who display a very different GI community to term infants. Certain characteristic patterns have been associated with negative health outcomes during the neonatal period, and these patterns may prove to have continual damaging effects if not resolved.

Results

In this st

SUBMITTER: Sim K 

PROVIDER: S-EPMC9841687 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature