Perioperative changes in fluid distribution and haemodynamics in acute high-risk abdominal surgery.

ABSTRACT:

Background

Understanding the pathophysiology of fluid distribution in acute high-risk abdominal (AHA) surgery is essential in optimizing fluid management. There is currently no data on the time course and haemodynamic implications of fluid distribution in the perioperative period and the differences between the surgical pathologies.

Methods

Seventy-three patients undergoing surgery for intestinal obstruction, perforated viscus, and anastomotic leakage within a well-defined perioperative regime, including intraoperative goal-directed therapy, were included in this prospective, observational study. From 0 to 120 h, we measured body fluid volumes and hydration status by bioimpedance spectroscopy (BIA), fluid balance (input vs. output), preload dependency defined as a > 10% incr

SUBMITTER: Cihoric M 

PROVIDER: S-EPMC9841944 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature