Spontaneous brain activity abnormalities in migraine: A meta-analysis of functional neuroimaging.

ABSTRACT: Neuroimaging studies have demonstrated that migraine is accompanied by spontaneous brain activity alterations in specific regions. However, these findings are inconsistent, thus hindering our understanding of the potential neuropathology. Hence, we performed a quantitative whole-brain meta-analysis of relevant resting-state functional imaging studies to identify brain regions consistently involved in migraine. A systematic search of studies that investigated the differences in spontaneous brain activity patterns between migraineurs and healthy controls up to April 2022 was conducted. We then performed a whole-brain voxel-wise meta-analysis using the anisotropic effect size version of seed-based d mapping software. Complementary analyses including jackknife sensitivity analysis, heterogenei

SUBMITTER: Cai M 

PROVIDER: S-EPMC9842892 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature