The effect of hunger state on hypothalamic functional connectivity in response to food cues.

ABSTRACT: The neural underpinnings of the integration of internal and external cues that reflect nutritional status are poorly understood in humans. The hypothalamus is a key integrative area involved in short- and long-term energy intake regulation. Hence, we examined the effect of hunger state on the hypothalamus network using functional magnetic resonance imaging. In a multicenter study, participants performed a food cue viewing task either fasted or sated on two separate days. We evaluated hypothalamic functional connectivity (FC) using psychophysiological interactions during high versus low caloric food cue viewing in 107 adults (divided into four groups based on age and body mass index [BMI]; age range 24-76 years; BMI range 19.5-41.5 kg/m² ). In the sated compared to the fasted con

SUBMITTER: Kullmann S 

PROVIDER: S-EPMC9842901 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature