Recent advances in genetic tools for engineering probiotic lactic acid bacteria.

ABSTRACT: Synthetic biology has grown exponentially in the last few years, with a variety of biological applications. One of the emerging applications of synthetic biology is to exploit the link between microorganisms, biologics, and human health. To exploit this link, it is critical to select effective synthetic biology tools for use in appropriate microorganisms that would address unmet needs in human health through the development of new game-changing applications and by complementing existing technological capabilities. Lactic acid bacteria (LAB) are considered appropriate chassis organisms that can be genetically engineered for therapeutic and industrial applications. Here, we have reviewed comprehensively various synthetic biology techniques for engineering probiotic LAB strains, such as clust

SUBMITTER: Mugwanda K 

PROVIDER: S-EPMC9842951 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature