Precision medicine in laryngeal cancer: protocol of the laryngeal cancer cohort (LARCH).

ABSTRACT:

Introduction

Laryngeal cancer disproportionately affects socioeconomically disadvantaged patients. Treatment can render a patient nil by mouth or in need of a permanent tracheostomy. In the past 30 years, survival has remained at best static and at worst it has declined. Currently, there is no method of prognosticating how a patient will respond to treatment.The LARyngeal Cancer coHort (LARCH) aims to establish how survival and quality-of-life outcomes compare between surgery and (chemo)radiotherapy in early and advanced laryngeal cancer and how the presenting features of laryngeal cancer influence oncological, functional and quality-of-life outcome.

Methods and analysis

This study is the first enhanced laryngeal cancer disease cohort. In the initial phase, we aim to deliver

SUBMITTER: Hamilton DW 

PROVIDER: S-EPMC9843189 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature