The factors of fiducial marker motions and individual margin assessment in postoperative breast cancer radiotherapy.

ABSTRACT:

Background

As a surrogate for the breast tumor bed, individual fiducial markers frequently move during radiotherapy. This study aimed to classify the motions and calculate the individualized target margin.

Methods

The mammary basal diameters (D) and heights (H) were measured to represent breast sizes for 15 patients after breast-conserving surgery. The clinical target volume (CTV) was divided into 4 quadrants by a coordinate system with the center of mass of the tumor bed as the origin. The lateral, anteroposterior, and craniocaudal motions of markers were calculated (M_LR, M_AP, M_SI) based on the difference of the setup errors between the spine matching and the fiducial markers matching. The distances between markers and the innermost, foremos

SUBMITTER: Luo J 

PROVIDER: S-EPMC9843309 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature