Stereotactic ablative radiation therapy for renal cell carcinoma with inferior vena cava tumor thrombus.

ABSTRACT:

Background

Inferior vena cava tumor thrombus (IVC-TT) is a rare yet deadly sequel of renal cell carcinoma (RCC) with limited treatment options. The standard treatment is extirpative surgery, which has high rates of morbidity and mortality. As a result, many patients are unfit or unwilling to undergo surgery and face poor prognosis. This stresses the need for alternative options for local disease control. Our study aims to assess the feasibility and oncological outcomes of stereotactic ablative radiation (SAbR) for IVC-TT.

Methods

A retrospective study reviewing six leading international institutions' experience in treating RCC with IVC-TT with SAbR. Primary end point was overall survival using Kaplan-Meier.

Results

Fifteen patients were included in the cohort. Over 50

SUBMITTER: Freifeld Y 

PROVIDER: S-EPMC9843697 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature