Baseline cardiac function checkup in patients with gastric or breast cancer receiving trastuzumab or anthracyclines.

ABSTRACT:

Background

Although trastuzumab and anthracyclines are frequently used to treat breast cancer (BC) and gastric cancer (GC), cardiotoxicity is a serious concern. The cardiac function assessment is recommended at baseline before initiating treatment. However, the prevalence rates of baseline cardiac checkups are unknown.

Methods

The national database of hospital-based cancer registries linked to the health services-utilization data was used to study patients with newly diagnosed stage IV BC and GC (n = 6271) who received trastuzumab (n = 4324, 69.0%) or anthracyclines between January 2012 and December 2015. The baseline ultrasound echocardiogram (UCG) performance rate and factors related to adequate UCG performance for all patients and those receiving trastuzumab were analyzed

SUBMITTER: Ishii T 

PROVIDER: S-EPMC9844617 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature