The association between single nucleotide polymorphisms and ovarian cancer risk: A systematic review and network meta-analysis.

ABSTRACT:

Background

The relationship between single nucleotide polymorphisms (SNPs) and ovarian cancer (OC) risk remains controversial. This systematic review and network meta-analysis was aimed to determine the association between SNPs and OC risk.

Methods

Several databases (PubMed, EMBASE, China National Knowledge Infrastructure, Wanfang databases, China Science and Technology Journal Database, and China Biology Medicine disc) were searched to summarize the association between SNPs and OC published throughout April 2021. Direct meta-analysis was used to identify SNPs that could predict the incidence of OC. Ranking probability resulting from network meta-analysis and the Thakkinstian's algorithm was used to select the most appropriate gene model. The false positive report probabilit

SUBMITTER: Hu J 

PROVIDER: S-EPMC9844622 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature