Association of plasma acylcarnitines and amino acids with hypertension: A nationwide metabolomics study.

ABSTRACT:

Background

Identification of metabolomics profile in subjects with different blood pressure, including normal blood pressure, elevated blood pressure, stage 1 hypertension, and stage 2 hypertension, would be a promising strategy to understand the pathogenesis of hypertension. Thus, we conducted this study to investigate the association of plasma acylcarnitines and amino acids with hypertension in a large Iranian population.

Methods

1200 randomly selected subjects from the national survey on the Surveillance of Risk Factors of Non-Communicable Diseases in Iran (STEPs 2016) were divided into four groups based on the ACC/AHA hypertension criteria: normal blood pressure (n = 293), elevated blood pressure (n = 135), stage 1 hypertension (n = 325), and stage 2 hypertension (n = 44

SUBMITTER: Arjmand B 

PROVIDER: S-EPMC9844860 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature