Correlation study of FGF23/D-serine in maintenance hemodialysis patients with combined hearing impairment.

ABSTRACT:

Background

Recent studies have reported an association between chronic renal failure and hearing impairment. Yet, the exact mechanism of action is still not fully understood. In this study, we investigated the expression of fibroblast growth factor 23 (FGF23) and D-serine in maintenance hemodialysis (MHD) patients with end-stage renal disease (ESRD) complicated with hearing impairment and further investigated the correlation between FGF23/D-serine and hearing impairment.

Methods

A total of 90 subjects, including 30 MHD patients complicated with hearing impairment, 30 MHD patients with normal hearing, and 30 controls, were included in this case-control study. Relevant data were obtained by questionnaire survey, audiometric test, enzyme-linked immunosorbent assay (ELISA) to de

SUBMITTER: Yuan D 

PROVIDER: S-EPMC9844913 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature