Open and reusable annotated mass spectrometry dataset of a chemodiverse collection of 1,600 plant extracts.

ABSTRACT: As privileged structures, natural products often display potent biological activities. However, the discovery of novel bioactive scaffolds is often hampered by the chemical complexity of the biological matrices they are found in. Large natural extract collections are thus extremely valuable for their chemical novelty potential but also complicated to exploit in the frame of drug-discovery projects. In the end, it is the pure chemical substances that are desired for structural determination purposes and bioactivity evaluation. Researchers interested in the exploration of large and chemodiverse extract collections should thus establish strategies aiming to efficiently tackle such chemical complexity and access these structures. Establishing carefully crafted digital layers documenting the sp

SUBMITTER: Allard PM 

PROVIDER: S-EPMC9845059 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature