Early prenatal exposure to air pollutants and congenital heart disease: a nested case-control study.

ABSTRACT:

Background

Congenital heart disease (CHD) is one of the most common congenital malformations in humans. Inconsistent results emerged in the existed studies on associations between air pollution and congenital heart disease. The purpose of this study was to evaluate the association of gestational exposure to air pollutants with congenital heart disease, and to explore the critical exposure windows for congenital heart disease.

Methods

The nested case-control study collected birth records and the following health data in Tianjin Women and Children's Health Center, China. All of the cases of congenital heart disease from 2013 to 2015 were selected matching five healthy controls for each case. Inverse distance weighting was used to estimate individual exposure based on daily air

SUBMITTER: Ma Z 

PROVIDER: S-EPMC9845069 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature