Preparation of collagen fibrils from mineralized tissues and evaluation by atomic force microscopy.

ABSTRACT: Mineralized tissues like bone and dentin are materials that support the distribution of mechanical loads through the body of humans and other animals. While their organic content plays a critical role on the structural behavior of these materials, investigations that quantify the structural properties of collagen fibrils in mineralized tissues at the nanoscale are rather limited. We report a new experimental methodology to prepare samples of dentinal collagen fibrils for evaluation by atomic force microscopy and characterize their mechanical behavior. Specifically, a Dynamic Mechanical Analysis (DMA) of the collagen fibrils was performed to study their viscoelastic behavior. The capacity for viscous dampening in the fibrils was characterized in terms of measures of the energy dissipation,

SUBMITTER: Ryou H 

PROVIDER: S-EPMC9845140 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature