Organic amendment treatments for antimicrobial resistance and mobile element genes risk reduction in soil-crop systems.

ABSTRACT: Agricultural fertilization with organic amendments of animal origin often leads to antibiotic resistance dissemination. In this study, we evaluated the effect of different treatments (anaerobic digestion, biochar application, ozonation, zerovalent iron nanoparticle application, and spent mushroom substrate addition) on the resistome in dairy cow manure-derived amendments (slurry, manure, and compost). Anaerobic digestion and biochar application resulted in the highest reduction in antibiotic resistance gene (ARG) and mobile genetic element (MGE) gene abundance. These two treatments were applied to cow manure compost, which was then used to fertilize the soil for lettuce growth. After crop harvest, ARG and MGE gene absolute and relative abundances in the soil and lettuce samples were determ

SUBMITTER: Jauregi L 

PROVIDER: S-EPMC9845208 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature